Restless legs syndrome (RLS) is a neurosensory disorder first described by Sir Thomas Willis in 1672. As early as the 19th century, Theodor Wittmaack1 observed the comorbidity of RLS with depression and anxiety. He termed this condition 'anxietas tibiarum,' and believed it to be a form of hysteria.
Once thought to be rare, data now suggest that RLS is relatively common but underrecognized and undertreated.2 Several clinical and population-based studies have reported a high prevalence of psychiatric comorbidities-particularly depression and anxiety-in patients with RLS.3 Thus, for psychiatrists, understanding the clinical features and treatment of RLS has become critical in their daily practice. However, the symptomatic overlap between RLS and mood disorders and the potential impact of psychiatric medications on RLS symptoms make RLS a diagnostic and treatment challenge.
This article provides an overview of the clinical features of and treatment strategies for RLS. It also offers a survey of the current literature on issues in the diagnosis and treatment of RLS among psychiatric patients.
CME, 1.5 Credits Sep 01, 2009